UPS1
Sigma
Universal Proteomics Standard Set
Description
| Application | It may be used to standardize and/or evaluate mass spectrometric (e.g., LC-MS/MS, MALDI-TOF-MS, etc.) and electrophoretic analysis conditions prior to the analysis of complex protein samples. • It may be used to bracket critical experimental datasets, thereby confirming the robustness of the analysis method. • Laboratories generating or comparing data derived from poorly defined samples may use it as an external reference to assist with the evaluation of results. • It may facilitate the comparison of mass spectrometric or other proteomic data that is generated in different labs using a variety of analytical strategies and instruments. • It may potentially help identify limitations of proteomics analysis systems and search algorithms. |
| Features and Benefits | Discover the Benefits for Yourself! • Test the power of your analytical strategy • Troubleshoot and optimize your analytical protocol • Confirm system suitability before analyzing critical samples • Normalize analytical results day to day or lab to lab |
| General description | The Universal Proteomics Standard (UPS) Set was developed in collaboration with the Association of Biomolecular Resource Facilities (ABRF) Proteomics Standards Research Group (sPRG). This protein mixture was extensively evaluated and reported under the direction of the Association of Biomolecular Resource Facilities (ABRF) Proteomics Standards Research Group (sPRG) during a comprehensive 2005/2006 study. The findings of the study were presented at the ABRF 2006 and US HUPO 2006 conferences. |
Properties
| storage temp. | −20°C |
Safety
| Hazard Codes | Xn,B |
| Risk Statements | 36/37/38-42 |
| Safety Statements | 23-26-45 |
Components
| Kit component only | Universal Proteomics Standard 1 vial |
| Kit component also available separately | Trypsin from porcine pancreas, Proteomics Grade, Dimethylated 20 ug T6567 |
Related Products
| Related product | UPS2, Proteomics Dynamic Range Standard Set |
References
| reference | Nkemdilim C. Uwaje, et al. Electrophoresis, 2007. May 22; 28 (12): 1867-1874., Interrogation MS/MS search data with an pl Filter algorithm to increase protein indetification success Electrophoresis |
| David L. Tabb, Christopher G. Fernando, and Matthew C. Chambers, MyriMatch: Highly Accurate Tandem Mass Spectral Peptide Indentification by Multivariate Hypergeometric Analysis J. Protein Res 6, 654-661, (2007) | |
Tabb, D.L., et al., MyriMatch: highly accurate tandem mass spectral peptide identification by multivariate hypergeometric analysis. J. Proteome Res. 6, 654-661, (2007) Abstract |
